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hmw poly i c lyovec  (InvivoGen)


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    InvivoGen hmw poly i c lyovec
    Hmw Poly I C Lyovec, supplied by InvivoGen, used in various techniques. Bioz Stars score: 96/100, based on 609 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/hmw poly i c lyovec/product/InvivoGen
    Average 96 stars, based on 609 article reviews
    hmw poly i c lyovec - by Bioz Stars, 2026-06
    96/100 stars

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    Microglia phagocytic activity and antigen cross presentation triggered by treatment with mock, poly(I:C), recombinant IFN γ , and PVSRIPO. The phagocytosis/cross presentation assay template with microglia exposure to B16 OVA , described in , was repeated with juxtaposing PVSRIPO to mock, (transfected) poly(I:C), and recombinant IFNγ. Phagocytosis of CD11b + -bead-isolated, hCD155 -tg mouse microglia was determined by flow cytometry analyses of CT-label (A , C) ; antigen cross presentation was tested by flow cytometry for H2Kb:SIINFEKL complexes (B , C) ; cells were tested 0h, 24h, 48h and 72h post treatment; flow cytometry histograms for phagocytosis/cross presentation at 48h and 72h post treatment are shown (C) . (A , B) Data were analyzed by Shapiro-Wilk test and 2-way ANOVA with multiple comparisons.

    Journal: bioRxiv

    Article Title: Viral Microglia Reprogramming Clears Oligomeric Neurotoxic Debris

    doi: 10.64898/2026.04.06.716590

    Figure Lengend Snippet: Microglia phagocytic activity and antigen cross presentation triggered by treatment with mock, poly(I:C), recombinant IFN γ , and PVSRIPO. The phagocytosis/cross presentation assay template with microglia exposure to B16 OVA , described in , was repeated with juxtaposing PVSRIPO to mock, (transfected) poly(I:C), and recombinant IFNγ. Phagocytosis of CD11b + -bead-isolated, hCD155 -tg mouse microglia was determined by flow cytometry analyses of CT-label (A , C) ; antigen cross presentation was tested by flow cytometry for H2Kb:SIINFEKL complexes (B , C) ; cells were tested 0h, 24h, 48h and 72h post treatment; flow cytometry histograms for phagocytosis/cross presentation at 48h and 72h post treatment are shown (C) . (A , B) Data were analyzed by Shapiro-Wilk test and 2-way ANOVA with multiple comparisons.

    Article Snippet: Microglia were plated at 70% confluency and infected with PVSRIPO (MOI 10) or mock (DMEM), recombinant mouse IFNγ (200 U/ml; R&D Systems, #485-MI), or poly(I:C) (10 μg/ml; Invivogen, high molecular weight polyinosine:polycytidylic acid; LyoVec TM complexed, #tlrl-piclv) and incubated with 200,000 UV-irradiated cells for the duration of the intervals shown in the figures.

    Techniques: Activity Assay, Recombinant, Transfection, Isolation, Flow Cytometry